by Dr Imtiyaz Thagia,
Teacher of Science
Teacher of Science
DNA is essential to human life - making us who we are. These long molecules are made up of twisted strands of the bases A, T, C and G. A genetic disease is caused by aberrations within an individual’s DNA. This can range from a discrete mutation in a single base in the DNA of a single gene to a gross chromosome abnormality involving the addition or subtraction of an entire chromosome or set of chromosomes. Examples of genetic diseases include Huntington's, Sickle Cell Anaemia and Cystic Fibrosis.
Pupils used Jelly Beans to model the structure of DNA, demonstrating how bases join to form DNA strands. Pupils were then able use the model to understand how mutations within the DNA sequence can lead to genetic diseases.
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